SKU: 364215375135191

Metabolomics Spotlight

Name: Metabolomics Spotlight
SKU: 364215375135191

$239.00

Excluding Sales Tax

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The Metabolomics Spotlight test provides an in-depth analysis of the function & efficiency of multiple aspects of an individual's unique biochemistry.  This information allows you to understand your metabolic pathways & reveals your unique metabolic state.

Discover your unique metabolic signature with Designs for Health Metabolomics Spotlight™ functional wellness test.

The Metabolomics Spotlight functional wellness test analysis provides an in-depth view of the function and efficiency of multiple aspects of an individual’s unique biochemistry and metabolism. This analysis will assist practitioners in unraveling their client’s metabolic pathways and revealing their metabolic status.

Metabolomix Spotlight test kit which examines:

Metabolic & macronutrient processing

Mitochondrial function & micronutrient status

Amino acid, protein, & neurotransmitter metabolism

Inflammatory response & oxidative stress

Detoxification & microbial metabolites

Stress, mood & overall well-being

Access to view your Functional Wellness test results through the Well World app.

The Designs for Health Spotlight tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid or other medical insurance. These tests are not available for purchase in New York or US Territories.

This is a urinary metabolites test. In order to get the most accurate baseline interpretation of how your body functions, it is important to eliminate factors that can influence your results. In general, it is helpful to stop all supplements seven days prior to collecting your sample.

Detailed collection instructions will be provided in your kit, but please read below about other factors which may influence your results.

It is highly recommended that you schedule a Wellness Consultation to review your results with our provider.

Artificial sweeteners and MSG	Artificial sweeteners and MSG are composed of amino acids which can directly impact measured amino acid levels
Eat your usual diet; avoid over-consuming any single food, extreme diets, or engaging in a rigourous activity (i.e. marathon)	Extreme diets and activity may impact certain organic acid biomarkers related to the citric acid cycle, neurotransmitter metabolites, dysbiosis markers, or amino acids
Phenol and flavonoid containing compounds in fruits, vegetables, chocolate, and tea can result in elevation of certain bacterial and fungal dysiosis markers on the organic acids profile
Bananas, pineapple, kiwi, plums, avacado, walnuts, and pecans can result in an elevation of the serotonin metabolite 5-HIAA measured on the organic acids profile
Seafood	Seafood containing heavy metals such as mercury and arsenic can result in a transient elevation
Six 8-ounce glasses of fluid	Creatinine concentration is influenced by fluid intake
Fasting, water allowed only	Reference ranges were set based on an overnight-fasted population. Overnight fasting minimizes influence of a single meal and provides a "steady diet" sample

Medications and supplements may impact results. The discontinuation of any medication is at the discretion of the clinician, only if medically appropriate.

Medications and Supplements	Possible Impact on Results
Valproic acid	Direct assay interferent for organic acid xanthurenic acid
Acetaminophen	Direct assay interferent for multiple organic acids
Berberine HCl	Direct assay interferent for organic acids IAA and 5-HIAA
Antibiotics, antifungals, probiotics, digestive enzymes, acid blocking medications	May indirectly influence urinary organic acid markers of malabsorption/dysbiosis Amino acid levels may be impacted by aminoglycoside antibiotics
Amphetamines, centrally acting medications, antidepressants, Anti-Parkinsonian medications	May influence urinary organic acid markers of neurotransmitter metabolism1,2
HMG-CoA-reductase inhibitors (statins) and red yeast rice	May indirectly increase urinary organic acid B-methylglutaric acid levels
N-Acetyl Cysteine (NAC)	Direct assay interferent for cholesterol and triglycerides add-on tests; may lead to falsely low results
Oral contraceptives, estrogen therapy	May increase the organic acid quinolinic acid excretion both from altered tryptophan metabolism directly, as well as the indirect functional vitamin B6 insufficiency3
Quercetin	May elevate the organic acid homovanillic acid4
Steroids	May lower inflammatory neurotransmitter metabolite quinolinic acid, an organic acid
Diuretics	May impact creatinine concentration, thus affecting all urinary biomarker measurements
Fibrates	May influence fatty acid levels In some animal studies, fibrates also impact cellular energy metabolites on the organic acids profile
Kreb's cycle and amino chelated supplements (i.e. citrate, malate, succinate, glycinate, threonate, and orotate forms of supplements [magnesium citrate], alpha ketoglutarate, and others)	May result in elevations of corresponding Kreb's cycle markers and amino acids
Provocation/chelating agents (i.e. DMPS, DMSA, EDTA, etc.)	Reference ranges are based on a non-provoked, non-chelated patient population
Vitamin C	May increase urinary excretion of organic acid oxalic acid or lead

Dietary Influences on urinary organic acids:4-16

Urinary Metabolite	Common Dietary Sources
Indoleacetic acid	High tryptophan intake, green/black tea
Phenylacetic acid	Wine/grapes
Dihydroxyphenylpropionic acid	Whole-grains, chocolate, coffee, green/black tea, olives/olive oil, citrus fruits (animal studies)
3-Hydroxyphenylacetic acid & 4-hydroxyphenlyacetic acid	Wine/grapes, cranberries, green/black tea, berries, orange juice, grape seed extract
Benzoic acid/Hippuric acid	Orange juice, elderberry, huckleberry, food preservative, berries, other flavonoids
Citramalic acid	Apples, cranberries, sugar beets
Tartaric acid	Wine/grapes, chocolate, food additive/preservative
Malic acid	Fruits (apples, pears), vegetables, throat lozenges, syrups, beverages with food preservatives and additives
Homovanillic acid	Flavanols including tomatoes, onions and tea
5-hydroxyindolacetic acid	Bananas, plantains, kiwi, pineapple, nuts, and tomatoes

Metabolomics Spotlight

This test includes:

RETURN & REFUND POLICY

SHIPPING INFO

COLLECTION INSTRUCTIONS

SAMPLE REPORT